Topical corticosteroids can be absorbed from normal, intact skin. Betamethasone valerate, the 17-valerate ester of betamethasone, has been shown to provide anti-inflammatory and antipruritic activity in the topical management of corticosteroid-responsive otitis externa. Betamethasone, an analog of prednisolone, has a high degree of corticosteroid activity and a slight degree of mineralocorticosteroid activity. Specifically, gentamicin is active against the following organisms commonly isolated from canine ears: Staphylococcus aureus, other Staphylococcus spp., Pseudomonas aeruginosa, Proteus spp., and Escherichia coli.īetamethasone: Betamethasone valerate is a synthetic adrenocorticoid for dermatologic use. In vitro tests have determined that gentamicin is bactericidal and acts by inhibiting normal protein synthesis in susceptible microorganisms.
Gentamicin: Gentamicin sulfate is an aminoglycoside antibiotic active against a wide variety of pathogenic gram-negative and gram-positive bacteria.
DescriptionĮach gram of OTOMAX ointment contains gentamicin sulfate, equivalent to 3 mg gentamicin base betamethasone valerate, equivalent to 1 mg betamethasone and 10 mg clotrimazole, in a mineral oil-based system containing a plasticized hydrocarbon gel. Keep this and all drugs out of the reach of children. (GENTAMICIN SULFATE, BETAMETHASONE VALERATE AND CLOTRIMAZOLE, OINTMENT)ĬAUTION: Federal law restricts this drug to use by or on the order of a licensed veterinarian.
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